[Initial results of combined surgical-medical therapy for metastatic cancer of the stomach].

Abstract

Fifty patients with advanced gastric cancer underwent chemotherapy in accordance with the FAMTX protocol. Complete tumor remission was achieved in 6 patients and partial remission in 11 patients. In this group 9 patients (tumor stage: T3-4, N2-3, M chi-1) underwent a second-look operation after chemotherapy either to confirm the complete remission or to resect the remaining tumor mass. It is concluded that even in advanced stages of gastric carcinomas a more aggressive approach involving a combination of surgical and chemotherapeutic treatment improves the survival time of these patients.

• Authors: D Henne-Bruns, B Kremer, H J Weh
• Journal: Helvetica chirurgica acta (Helv Chir Acta) Vol. 57 Issue 1 Pg. 73-6 (Jun 1990) ISSN: 0018-0181 [Print] Switzerland
• Vernacular Title: Erste Ergebnisse eines kombinierten chirurgisch-onkologischen Therapiekonzeptes beim metastasierenden Magenkarzinom.
• PMID: 1699913 (Publication Type: English Abstract, Journal Article)

Chemical References

• Doxorubicin
• Fluorouracil
• Methotrexate

Topics

• Adult
• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Doxorubicin (administration & dosage)
• Female
• Fluorouracil (administration & dosage)
• Gastrectomy
• Humans
• Male
• Methotrexate (administration & dosage)
• Middle Aged
• Neoplasm Metastasis
• Palliative Care
• Reoperation
• Stomach Neoplasms (drug therapy, surgery)