[Rheological therapeutic effects in diseases of the inner ear].

Abstract

The aim of the rheological treatment in sudden deafness is the improvement of the microcirculation in the inner ear by hemodilution and decreased viscosity of the blood. Both parameters have been checked in two groups of patients suffering from sudden deafness; one treated with Dextran-40 and Pentoxifylline, the other with Dextran-40 only. Improvement of rheological characteristics of blood was statistically significant in the combined therapy with Dextran-40 and Pentoxifylline. Two cohorts of sudden deafness patients--one selected, one non selected--treated with Pentoxifylline and Dextran 40 have been evaluated in respect of hearing improvement under this rheological results compared with the spontaneous remission rate given by Weinaug in 1984.

• Authors: K Hörmann, M Bernal Sprekelsen
• Journal: Anales otorrinolaringologicos ibero-americanos (An Otorrinolaringol Ibero Am) Vol. 17 Issue 4 Pg. 397-404 ( 1990) ISSN: 0303-8874 [Print] Spain
• Vernacular Title: Efectos terapéuticos reológicos en las enfermedades del oído interno.
• PMID: 1699442 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Dextrans
• Pentoxifylline

Topics

• Adult
• Blood Viscosity (drug effects)
• Cochlea (blood supply)
• Dextrans (therapeutic use)
• Drug Evaluation
• Drug Therapy, Combination
• Female
• Hearing Loss (drug therapy, etiology)
• Humans
• Hypoxia (complications)
• Male
• Microcirculation (drug effects)
• Middle Aged
• Pentoxifylline (therapeutic use)
• Regional Blood Flow (drug effects)