Is digoxin a drug of the past?

Abstract	Digoxin has been the cornerstone of the treatment of heart failure for more than 2 centuries. Now that newer therapies have been introduced that reduce the mortality rate in heart failure and recent trials have failed to prove the same for digoxin, its use has significantly decreased. But a careful review of the multiple pharmacologic actions of digoxin and closer analysis of the results of recent trials suggest that digoxin may in fact continue to be an effective treatment for heart failure.
Authors	Mohammad Hassan Pervaiz, Michael G Dickinson, Mohamad Yamani
Journal	Cleveland Clinic journal of medicine (Cleve Clin J Med) Vol. 73 Issue 9 Pg. 821-4, 826, 829-32 passim (Sep 2006) ISSN: 0891-1150 [Print] United States
PMID	16970134 (Publication Type: Journal Article, Review)
Chemical References	Cardiotonic Agents Digoxin
Topics	Atrial Fibrillation (drug therapy) Cardiotonic Agents (therapeutic use) Digoxin (therapeutic use) Heart Failure (drug therapy) Humans

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