Abstract | BACKGROUND: METHODS AND RESULTS: CONCLUSIONS: These experiments suggest that an antithrombotic approach based upon xyloside induction of circulating GAGs may have the potential to approximate the efficacy of warfarin and yet with a reduced risk to hemostasis.
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Authors | J R Toomey, M A Abboud, R E Valocik, P F Koster, C L Burns-Kurtis, K Pillarisetti, T M Danoff, J A Erhardt |
Journal | Journal of thrombosis and haemostasis : JTH
(J Thromb Haemost)
Vol. 4
Issue 9
Pg. 1989-96
(Sep 2006)
ISSN: 1538-7933 [Print] England |
PMID | 16961606
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Anticoagulants
- Glycosaminoglycans
- Glycosides
- Protamines
- xylosides
- Warfarin
- Heparin Cofactor II
- odiparcil
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Topics |
- Animals
- Anticoagulants
(adverse effects, therapeutic use)
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Glycosaminoglycans
(blood)
- Glycosides
(adverse effects, therapeutic use)
- Hemorrhage
(chemically induced)
- Heparin Cofactor II
- Protamines
(therapeutic use)
- Rats
- Vena Cava, Inferior
- Venous Thrombosis
(drug therapy)
- Warfarin
(adverse effects, therapeutic use)
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