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Successful treatment of acquired amegakaryocytic thrombocytopenia with cyclosporine in adult onset Still's disease.

AbstractAcquired amegakaryocytic thrombocytopenia (AAT) is a rare disorder, characterized by severe thrombocytopenia and selective, marked decrease or absence of megakaryocytes in the bone marrow. We describe a 29-year-old female with adult onset Still's disease preceding a diagnosis of AAT and autoimmune hemolytic anemia, which was successfully treated with cyclosporine. This is the first case of AAT in a patient with adult onset Still's disease.
AuthorsMin-Young Her, Tae-Hwan Kim, Hyun-Kyu Chang, Woong-Soo Lee, Dae-Hyun Yoo (Affiliation: Division of Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University, Seoul, 133-792, South Korea.)
JournalRheumatology international (Rheumatol Int) Vol. 27 Issue 3 Pg. 295-8 (Jan 2007) ISSN: 0172-8172 Germany
PMID16957888 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antirheumatic Agents
  • Cyclosporine
Topics
  • Adult
  • Anemia, Hemolytic, Autoimmune (complications, drug therapy)
  • Antirheumatic Agents (therapeutic use)
  • Cyclosporine (therapeutic use)
  • Female
  • Humans
  • Megakaryocytes (drug effects)
  • Platelet Transfusion
  • Still's Disease, Adult-Onset (complications, drug therapy)
  • Thrombocytopenia (complications, drug therapy)