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The effect of therapeutic ultrasound on angiogenesis.

Abstract
The effect of therapeutic ultrasound on the formation of new blood vessels in full-thickness excised lesions in the flank skin of adult rats was assessed quantitatively using microfocal x-ray techniques. Wounds were either sham-treated (control group) or exposed to ultrasound for 5 min daily at an intensity of 0.1 W/cm2 SATA (frequency either 0.75 MHz or 3.0 MHz). By 5 days after injury there were more blood vessels in equivalent regions of the granulation tissue of the ultrasound-treated wounds than in the control wounds. This suggested that the ultrasound-treated wounds were at a more advanced stage in the repair process. By 7 days after injury there was no significant difference in blood vessel number between the three groups.
AuthorsS R Young, M Dyson
JournalUltrasound in medicine & biology (Ultrasound Med Biol) Vol. 16 Issue 3 Pg. 261-9 ( 1990) ISSN: 0301-5629 [Print] England
PMID1694604 (Publication Type: Journal Article)
Topics
  • Animals
  • Female
  • Microradiography
  • Neovascularization, Pathologic
  • Rats
  • Rats, Inbred Strains
  • Skin (blood supply, injuries)
  • Ultrasonic Therapy
  • Wound Healing

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