Alzheimer Disease

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Also Known As:

Alzheimer's Disease; Senile Dementia; Early Onset Alzheimer Disease; Late Onset Alzheimer Disease; Primary Senile Degenerative Dementia; Presenile Dementia; Alzheimer Disease, Early Onset; Alzheimer Disease, Late Onset; Alzheimer Type Senile Dementia; Alzheimer's Disease, Focal Onset; Dementia, Presenile; Dementia, Primary Senile Degenerative; Focal Onset Alzheimer's Disease; Senile Dementia, Acute Confusional; Alzheimer Dementia, Presenile; Alzheimer Type Dementia; Dementia, Presenile Alzheimer; Dementias, Presenile; Dementias, Senile; Disease, Alzheimer; Disease, Alzheimer's; Presenile Dementias; Senile Dementias; Acute Confusional Senile Dementia; Dementia, Alzheimer Type; Dementia, Senile; Presenile Alzheimer Dementia; Senile Dementia, Alzheimer Type

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Nervous System Diseases: 3414

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Neurodegenerative Diseases: 7363

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Tauopathies: 302

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Alzheimer Disease: 25964

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Central Nervous System Diseases: 930

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Brain Diseases: 1120

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Dementia: 10685

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Alzheimer Disease: 25964

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Mental Disorders: 1709

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Cognitive Disorders Amnestic Dementia Delirium: 45

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Dementia: 10685

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Alzheimer Disease: 25964

Authors	Calvin Hirsch (Affiliation: UC Davis Medical Center, Sacramento, California, USA.)
Journal	ACP journal club (ACP J Club) 2006 Sep-Oct Vol. 145 Issue 2 Pg. 50 ISSN: 1056-8751 United States
PMID	16944870 (Publication Type: Comment, Journal Article)

Galantamine was effective in mild-to-moderate Alzheimer disease.