HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Effect of ammonium hexafluorosilicate on dentin tubule occlusion for the treatment of dentin hypersensitivity.

AbstractPURPOSE:
To evaluate the occluding ability of ammonium hexafluorosilicate (SiF).
METHODS:
Dentin disks prepared from human extracted teeth were grouped as follows to prepare different situations of dentin hypersensitivity: (1) those sonicated for 20 minutes; (2) those treated with 0.5 mol/L EDTA for 2 minutes; (3) those treated with 6% citric acid for 2 minutes; (4) those treated with 50% citric acid for 2 minutes. Then, SiF or diamine silver fluoride (AgF) was applied to the dentin disks and the dentin tubule occlusion was observed with scanning electron microscopy (SEM). The percent of open tubules before and after SiF or AgF treatment were measured by NIH image using SEM photographs. Also, the dentin permeability was measured.
RESULTS:
SEM micrographs demonstrated that the dentin tubules were completely occluded by the precipitate after SiF treatment. Also, the dentin permeability was reduced to 10.3%. In contrast, most of the dentin tubules remained open after AgF treatment. EDXA analysis showed that the precipitate in the dentin tubules that forms after SiF treatment contains Si, Ca and P, indicating a silica-calcium phosphate complex.
AuthorsToshiyuki Suge, Akiko Kawasaki, Kunio Ishikawa, Takashi Matsuo, Shigeyuki Ebisu
JournalAmerican journal of dentistry (Am J Dent) Vol. 19 Issue 4 Pg. 248-52 (Aug 2006) ISSN: 0894-8275 [Print] United States
PMID16939033 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Acids
  • Silicic Acid
  • hexafluorosilicate
  • Citric Acid
  • Edetic Acid
  • Fluorides
Topics
  • Acids (pharmacology)
  • Adult
  • Analysis of Variance
  • Citric Acid (pharmacology)
  • Dentin (drug effects, ultrastructure)
  • Dentin Permeability (drug effects)
  • Dentin Sensitivity (drug therapy)
  • Edetic Acid (pharmacology)
  • Fluorides (pharmacology)
  • Humans
  • Silicic Acid (pharmacology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: