Abstract | INTRODUCTION AND OBJECTIVES: METHODS: A model was developed to predict the cost-effectiveness of low-dose aspirin in the primary prevention of cardiovascular disease over a period of 10 years. The direct costs used were those of the Spanish National Health Service (NHS). Results were expressed as cost per life-year gained and per quality-adjusted life-year gained. RESULTS: Administering low-dose aspirin to an individual with a 10-year risk of coronary heart disease > or =15% resulted in an average net saving of e 797 (95% CI, e 263-1331) over the 10-year period, with savings starting in the first year. For an annual risk > or =0.24%, this form of treatment would reduce NHS costs. Treating all at-risk individuals in the Spanish population with aspirin would save e 26.5 million from the healthcare budget, starting in the first year. CONCLUSIONS: Administering low-dose aspirin to individuals with a 10-year risk of coronary heart disease > or =15% would result in significant cost savings for the Spanish NHS. Sensitivity analysis confirmed the robustness of these findings.
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Authors | Mark Lamotte, Carme Piñol, Carlos Brotons, Lieven Annemans, Elena Guardiola, Thomas Evers, Maria Kubin |
Journal | Revista espanola de cardiologia
(Rev Esp Cardiol)
Vol. 59
Issue 8
Pg. 807-15
(Aug 2006)
ISSN: 0300-8932 [Print] Spain |
Vernacular Title | Evaluación económica del tratamiento con ácido acetilsalicílico en dosis bajas en la prevención primaria de enfermedades cardiovasculares. |
PMID | 16938230
(Publication Type: English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Aspirin
(administration & dosage, economics)
- Budgets
- Cardiovascular Diseases
(economics, prevention & control)
- Cost-Benefit Analysis
- Female
- Humans
- Male
- Middle Aged
- Models, Economic
- Spain
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