Issues of antimicrobial resistance in group B streptococcus in the era of intrapartum antibiotic prophylaxis.

Abstract

The implementation of a culture screening-based approach to intrapartum antibiotic prophylaxis has been associated with substantial reduction in the incidence of early-onset group B streptococcal disease. Antibiotic prophylaxis is recognized as an interim strategy awaiting the licensure of a safe and effective conjugate vaccine for prevention of group B streptococcal infections in all susceptible populations. This article addresses concerns relating to antimicrobial resistance among group B streptococci that have arisen from use of intrapartum antibiotic prophylaxis and from increases in resistance in other gram-positive bacteria related genetically to group B streptococci.

• Authors: Morven S Edwards
• Journal: Seminars in pediatric infectious diseases (Semin Pediatr Infect Dis) Vol. 17 Issue 3 Pg. 149-52 (Jul 2006) ISSN: 1045-1870 [Print] United States
• PMID: 16934709 (Publication Type: Journal Article, Review)

Topics

• Antibiotic Prophylaxis
• Drug Resistance, Bacterial
• Female
• Humans
• Infant, Newborn
• Infant, Newborn, Diseases (microbiology, prevention & control)
• Infectious Disease Transmission, Vertical (prevention & control)
• Microbial Sensitivity Tests
• Pregnancy
• Pregnancy Complications, Infectious (microbiology)
• Streptococcal Infections (prevention & control)
• Streptococcus (drug effects, growth & development, isolation & purification)