[Necrotising cutaneous infections and necrotizing fasciitis: what antibiotic agents to use and how?].

Abstract

Antimicrobial therapy of complicated skin and soft tissue infections is guided by microbiological samplings performed in the preoperative period or during surgery. Antimicrobial treatment plays only an adjuvant role, the most important part of therapy is based on surgery. Systemic and local diffusion of antibiotic agents is poor. Cutaneous diffusion of antibiotics is delayed and incomplete. The most commonly administered treatments are betalactams agents combined to anti-anaerobes drugs such as nitroimidazoles, adapted to the location of infection. Prolonged duration of therapy is usually proposed.

• Authors: J-P Bédos
• Journal: Annales francaises d'anesthesie et de reanimation (Ann Fr Anesth Reanim) Vol. 25 Issue 9 Pg. 982-5 (Sep 2006) ISSN: 0750-7658 [Print] France
• Vernacular Title: Dermohypodermites bactériennes nécrosantes et fasciites nécrosantes: quels antibiotiques et comment?
• PMID: 16928422 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents

Topics

• Anti-Bacterial Agents (classification, therapeutic use)
• Fasciitis, Necrotizing (drug therapy)
• Humans
• Skin Diseases, Bacterial (drug therapy)