| Abstract | In neurology, paroxysmal syndromes are well-known, eg, as manifestations of multiple sclerosis. We report a patient with meningeal carcinomatosis, who presented with therapy-refractory nausea and vomiting. The clinical suspicion of a paroxysmal syndrome prompted a trial of carbamazepine, which resulted in complete cessation of the symptoms. In cancer patients with central nervous system (CNS) involvement and therapy-refractory symptoms with sudden onset, carbamazepine treatment should be considered. |
| Authors | Imke Strohscheer, Gian Domenico Borasio
(Affiliation: Section of Palliative Care, Medical University, Graz, Germany. imke.strohscheer at klinikum-graz.at)
|
| Journal | Palliative medicine
(Palliat Med)
Vol. 20
Issue 5
Pg. 549-50
(Jul 2006)
ISSN: 0269-2163 England |
| PMID | 16903409
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Anticonvulsants
- Antiemetics
- Carbamazepine
|
| Topics |
- Adult
- Anticonvulsants
(therapeutic use)
- Antiemetics
(therapeutic use)
- Breast Neoplasms
- Carbamazepine
(therapeutic use)
- Carcinoma
(drug therapy, secondary)
- Drug Resistance
- Fatal Outcome
- Female
- Humans
- Meningeal Neoplasms
(drug therapy, secondary)
- Nausea
(drug therapy, etiology)
- Syndrome
- Vomiting
(drug therapy, etiology)
|
