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Excimer laser versus narrow-band UVB (311 nm) in the treatment of psoriasis vulgaris.

AbstractBACKGROUND:
The excimer laser is a new therapeutic option in the treatment of psoriasis vulgaris.
OBJECTIVE:
The purpose of this study was to determine the response of psoriasis lesions to the 308-nm excimer laser compared to 311-nm UVB phototherapy.
METHODS:
In this prospective right/left comparative, open, single-blinded trial, selected psoriasis plaques of 16 patients were treated with the excimer laser whereas the rest of the body was treated with UVB narrow-band phototherapy. A modified PASI score was used to evaluate the results.
RESULTS:
After 12 treatments, 15 patients were evaluated. In 2 patients no difference between the two body sides was observed. In 9 patients the laser-treated lesions showed better results, whereas in 4 patients the side treated with 311-nm UVB showed more clearing. The mean reduction in PASI score was 5.6 and 4.9, respectively (difference not significant).
CONCLUSION:
The use of the 308-nm xenon chloride excimer laser is an additional effective therapeutic option for the treatment of psoriasis vulgaris.
AuthorsSimone Maria Goldinger, Reinhard Dummer, Peter Schmid, Mareike Prinz Vavricka, Gunter Burg, Severin Lauchli
JournalDermatology (Basel, Switzerland) (Dermatology) Vol. 213 Issue 2 Pg. 134-9 ( 2006) ISSN: 1018-8665 [Print] Switzerland
PMID16902290 (Publication Type: Journal Article, Randomized Controlled Trial)
CopyrightCopyright 2006 S. Karger AG, Basel.
Topics
  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Humans
  • Low-Level Light Therapy (methods)
  • Male
  • Middle Aged
  • Prospective Studies
  • Psoriasis (radiotherapy)
  • Single-Blind Method
  • Treatment Outcome

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