| Abstract | We reported two cases strongly suspected of ocular toxoplasmosis, in which a puncture of anterior eye chamber was performed for a final verification of clinical diagnosis. In both patients, fresh focal lesions of retinochoroiditis associated with old pigmented retinal scars were diagnosed. The 62-year-old women had a serological evidence of recently acquired T. gondii infection with an increasing IgG titre of a low avidity and a presence of specific IgM and IgA antibodies. In the 13-year-old girl, an immunological profile of the chronic infection was shown, confirmed by a high IgG avidity value. In the patient with a clinical picture of recurrent congenital toxoplasmosis, intraocular production of T. gondii-specific IgG was found in anterior eye chamber. The analysis of the specific antibodies synthesis in ocular fluid by the Western blot seems to be a valuable immunodiagnostic method for a final diagnosis of ocular toxoplasmosis. |
| Authors | M Paul, J Stefaniak, K Pecold, H Twardosz-Pawlik, E Kacprzak, W Rychlicki
(Affiliation: Klinika Chorób Pasozytniczych i Tropikalnych AM, 60-355 Poznań, ul. Przybyszewskiego 49.)
|
| Journal | Wiadomości parazytologiczne
(Wiad Parazytol)
Vol. 47 Suppl 1
Pg. 33-8
( 2001)
ISSN: 0043-5163 Poland |
| Vernacular Title | Analiza lokalnej syntezy swoistych immunoglobulin przeciwko Toxoplasma gondii w płynie z przedniej komory oka. Opis 2 przypadków. |
| PMID | 16897949
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Chemical References |
- Antibodies, Protozoan
- Immunoglobulins
|
| Topics |
- Adolescent
- Animals
- Antibodies, Protozoan
(analysis)
- Aqueous Humor
(immunology, parasitology)
- Chorioretinitis
(diagnosis, parasitology)
- Female
- Humans
- Immunoglobulins
(analysis)
- Middle Aged
- Recurrence
- Serologic Tests
- Toxoplasma
(isolation & purification)
- Toxoplasmosis, Congenital
(diagnosis, parasitology)
- Toxoplasmosis, Ocular
(diagnosis, parasitology)
|
