Basis of electrical stimulation of the cochlea and the cochlear nucleus.

Sensorineural hearing loss is the most common form of deafness in humans. In patients with a severe-profound sensorineural hearing loss therapeutic intervention can only be achieved by direct electrical stimulation of the auditory nerve via a cochlear implant, or - in cases where a cochlear implant is not a surgical option - neurons within the central auditory pathway via an auditory brainstem implant. This paper reviews the basis of electrical stimulation of these structures with an emphasis on pathophysiology and safety.
AuthorsRobert K Shepherd, Douglas B McCreery
JournalAdvances in oto-rhino-laryngology (Adv Otorhinolaryngol) Vol. 64 Pg. 186-205 ( 2006) ISSN: 0065-3071 [Print] Switzerland
PMID16891843 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review)
  • Animals
  • Brain Stem (physiology)
  • Cochlear Implants
  • Cochlear Nerve (pathology, physiology, physiopathology)
  • Cochlear Nucleus (anatomy & histology, physiology)
  • Electric Stimulation (methods)
  • Hearing Loss, Sensorineural (physiopathology, therapy)
  • Humans
  • Microelectrodes (adverse effects)
  • Safety
  • Treatment Outcome

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