HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Basis of electrical stimulation of the cochlea and the cochlear nucleus.

Abstract
Sensorineural hearing loss is the most common form of deafness in humans. In patients with a severe-profound sensorineural hearing loss therapeutic intervention can only be achieved by direct electrical stimulation of the auditory nerve via a cochlear implant, or - in cases where a cochlear implant is not a surgical option - neurons within the central auditory pathway via an auditory brainstem implant. This paper reviews the basis of electrical stimulation of these structures with an emphasis on pathophysiology and safety.
AuthorsRobert K Shepherd, Douglas B McCreery
JournalAdvances in oto-rhino-laryngology (Adv Otorhinolaryngol) Vol. 64 Pg. 186-205 ( 2006) ISSN: 0065-3071 [Print] Switzerland
PMID16891843 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review)
Topics
  • Animals
  • Brain Stem (physiology)
  • Cochlear Implants
  • Cochlear Nerve (pathology, physiology, physiopathology)
  • Cochlear Nucleus (anatomy & histology, physiology)
  • Electric Stimulation (methods)
  • Hearing Loss, Sensorineural (physiopathology, therapy)
  • Humans
  • Microelectrodes (adverse effects)
  • Safety
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: