[Occurrence of HIV antigens in patients with acquired immunodeficiency syndrome].

Abstract

A total of 74 serum samples from 37 AIDS patients were analysed for HIV antigen and results were correlated with duration of the disease, predominant symptoms, T4 lymphocyte count in peripheral blood, and antiviral therapy. The prevalence of HIV-Ag increased with duration of AIDS and T4 lymphocyte depletion. It was also higher in patients who were not treated with antiviral therapy than in treated persons. No correlation was found between HIV-Ag and clinical picture of AIDS. HIV antigenemia indicates a poor prognosis and can be regarded as an additional parameter of monitoring of AIDS patients.

• Authors: M Radkowski, T Laskus, E Kopicz-Kamińska, L Babiuch, J Slusarczyk
• Journal: Polskie Archiwum Medycyny Wewnetrznej (Pol Arch Med Wewn) Vol. 86 Issue 6 Pg. 366-71 (Dec 1991) Poland
• Vernacular Title: Wystepowanie antygenemii HIV u pacjentów z zespołem nabytego upośledzenia odporności.
• PMID: 1687897 (Publication Type: English Abstract, Journal Article)

Chemical References

• HIV Antigens

Topics

• Acquired Immunodeficiency Syndrome (immunology)
• Adult
• CD4-Positive T-Lymphocytes (immunology)
• HIV Antigens (analysis)
• Humans
• Leukocyte Count
• Male
• Middle Aged
• Monitoring, Physiologic
• Prognosis