[Coartem and fansimef in the treatment of falciparum malaria].

Abstract

From 2001 to 2003, anti-malarial combination coartem and fansimef, recommended by WHO, were used to treat falciparum malaria in Mali, 28 cases in each group. The mean fever clearance time, mean asexual parasite clearance time and the cure rate in 28 days were 35.3 +/- 6. 4, 34.7 +/- 6.9 hours and 100% respectively in coartem group, and 32. 6 +/- 5.8, 36.8 +/- 5.3 hours and 96.4% respectively in the fansimef group, with no significant difference between the two groups (P > 0.05).

• Authors: Wen-juan Shen, Moulaye Thiero
• Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases (Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi) Vol. 24 Issue 1 Pg. 26, V (Feb 28 2006) ISSN: 1000-7423 [Print] China
• PMID: 16866137 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Artemether, Lumefantrine Drug Combination
• Artemisinins
• Drug Combinations
• Ethanolamines
• Fluorenes
• mefloquine-sulfadoxine-pyrimethamine
• Sulfadoxine
• Mefloquine
• Pyrimethamine

Topics

• Abdominal Pain (chemically induced)
• Adolescent
• Artemether, Lumefantrine Drug Combination
• Artemisinins (adverse effects, therapeutic use)
• Child
• Child, Preschool
• Drug Combinations
• Drug Therapy, Combination
• Ethanolamines (adverse effects, therapeutic use)
• Female
• Fever (drug therapy, etiology)
• Fluorenes (adverse effects, therapeutic use)
• Humans
• Malaria, Falciparum (complications, drug therapy)
• Male
• Mali
• Mefloquine (adverse effects, analogs & derivatives, therapeutic use)
• Nausea (chemically induced)
• Pyrimethamine (adverse effects, therapeutic use)
• Skin (drug effects, pathology)
• Sulfadoxine (adverse effects, therapeutic use)
• Time Factors
• Treatment Outcome