| Abstract | A 39-year-old man was admitted to our hospital because of hyperthyroidism complicated with fever, atrial fibrillation with rapid ventricular response and congestive heart failure. Laboratory data revealed pancytopenia with a white blood cell count of 3360/microl, Hb 9.6 g/dl, and a platelet count of 88000/ul. After initiation of treatment with 30 mg of thiamazole daily, the patient's thyroid function improved but 4 weeks later, thiamazole induced agranulocytosis occurred and the drug was discontinued. After recovery from agranulocytosis, a subtotal thyroidectomy was performed, and the patient's pancytopenia rapidly improved. In this case, hyperthyroidism itself appeared to be closely related to the development of thrombocytopenia. |
| Authors | Akio Okamoto, Kyoko Taniguchi, Yoshihiro Kajita
(Affiliation: Department of Internal Medicine, Nantan General Hospital.)
|
| Journal | [RinshÅ ketsueki] The Japanese journal of clinical hematology
(Rinsho Ketsueki)
Vol. 47
Issue 6
Pg. 536-8
(Jun 2006)
ISSN: 0485-1439 Japan |
| PMID | 16862983
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Topics |
- Adult
- Graves Disease
(complications, physiopathology)
- Humans
- Hyperthyroidism
(surgery)
- Male
- Thrombocytopenia
(complications, physiopathology)
- Thyroid Gland
(physiopathology)
- Thyroidectomy
(methods)
|
