The role of surface PF4: glycosaminoglycan complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT).

• Authors: Mortimer Poncz, Lubica Rauova, Douglas B Cines
• Journal: Pathophysiology of haemostasis and thrombosis (Pathophysiol Haemost Thromb) Vol. 35 Issue 1-2 Pg. 46-9 ( 2006) ISSN: 1424-8832 [Print] Switzerland
• PMID: 16855346 (Publication Type: Journal Article)

Chemical References

• Glycosaminoglycans
• Platelet Factor 4
• Heparin

Topics

• Animals
• Blood Platelets (physiology)
• Glycosaminoglycans (metabolism, physiology)
• Heparin (adverse effects)
• Humans
• Platelet Factor 4 (immunology, metabolism, physiology)
• Protein Binding
• Thrombocytopenia (chemically induced, etiology)