Panniculitis, polyarthritis and osteomyelitis associated with pancreatic neoplasia in two dogs.

A 12-year-old crossbred dog (case 1) and a 12-year-old Shetland sheepdog (case 2) were presented with a history of lameness and distal limb swelling. Physical examination revealed joint effusions and asymmetrical swellings of the extremities. In case 1, a diagnosis of arthritis and cellulitis was made on fine-needle aspiration biopsy of the synovium and subcutis. In case 2, bone biopsies and synovial aspirates diagnosed osteomyelitis and arthritis. A diagnosis of pancreatic disease was made on the findings of marked elevations of serum lipase concentrations and ultrasonographic identification of pancreatic masses in both cases. Both the cases were non-responsive to symptomatic management and were subsequently euthanased. Postmortem examination confirmed the diagnosis of panniculitis, arthritis and osteomyelitis in both cases. A pancreatic exocrine adenoma was identified in case 1 and a pancreatic adenocarcinoma with widespread metastases in case 2. To the authors' knowledge the association of panniculitis, polyarthritis and osteomyelitis with pancreatic disorders has not been reported previously in canine clinical cases.
AuthorsR N A Gear, N J Bacon, S Langley-Hobbs, P J Watson, N Woodger, M E Herrtage
JournalThe Journal of small animal practice (J Small Anim Pract) Vol. 47 Issue 7 Pg. 400-4 (Jul 2006) ISSN: 0022-4510 [Print] England
PMID16842278 (Publication Type: Case Reports, Journal Article)
  • Adenoma (complications, diagnosis, veterinary)
  • Animals
  • Arthritis (diagnosis, etiology, veterinary)
  • Biopsy, Fine-Needle (veterinary)
  • Dog Diseases (diagnosis, etiology)
  • Dogs
  • Fatal Outcome
  • Female
  • Male
  • Osteomyelitis (diagnosis, etiology, veterinary)
  • Pancreatic Neoplasms (complications, diagnosis, veterinary)
  • Panniculitis (diagnosis, etiology, veterinary)
  • Synovial Membrane (pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: