[Clinical study on treatment of chronic superficial gastritis with jinghua weikang capsule].

Abstract

OBJECTIVE:

To observe the clinical efficacy and safety of Jinghua Weikang Capsule (JWC) on chronic gastritis (CG).

METHODS:

Ninety patients with CG were randomly divided into 3 groups: the control group treated with domperidone 10 mg, 3 times per day orally, the high and low-dose JWC groups treated with JWC 160 mg and 80 mg respectively 3 times per day. The therapeutic course for all groups was 14 days. Dyspeptic symptom score, gastric emptying rate and quality of life (QOL) in patients were observed.

RESULTS:

Dyspeptic symptom score was 19.97 +/- 1.85 and 24.40 +/- 1.85 after treatment in high and low-dose JWC groups respectively, lower than that before treatment (28.33 +/- 1.88 and 27.70 +/- 1.68, P <0.05); QOL improved obviously in all the three groups, among which the high-dose JWC group showed the best effect. The adverse reaction of JWC was very mild.

CONCLUSION:

JWC is an effective and safe drug for alleviating dyspeptic symptoms in patients with CG, its effect is more evident when high dose is applied.

• Authors: Juan Zeng, Xiu-li Zuo, Wei Wei
• Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 26 Issue 6 Pg. 517-20 (Jun 2006) ISSN: 1003-5370 [Print] China
• PMID: 16841668 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Capsules
• Drugs, Chinese Herbal

Topics

• Adolescent
• Adult
• Capsules
• Chronic Disease
• Drugs, Chinese Herbal (therapeutic use)
• Female
• Gastritis (drug therapy)
• Humans
• Male
• Middle Aged
• Phytotherapy