[A double-blind study on the effect of dexetimide in the control of neuroleptic-induced extrapyramidal side-effects].

Abstract

A double-blind study was carried out on the therapeutic effects of dexetimide and artane in the control of neuroleptic-induced extrapyramidal side-effects in 261 cases of schizophrenia. The authors found that therapeutic effects of two drugs for the control of extrapyramidal signs were equal. Dexetimidal had the advantages of less side-effects, less dosage and long-action.

• Authors: Y Chen
• Journal: Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry (Zhonghua Shen Jing Jing Shen Ke Za Zhi) Vol. 24 Issue 4 Pg. 197-9, 251 (Aug 1991) ISSN: 0412-4057 [Print] China
• PMID: 1683277 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Antipsychotic Agents
• Dexetimide
• Trihexyphenidyl

Topics

• Adolescent
• Adult
• Antipsychotic Agents (adverse effects)
• Dexetimide (therapeutic use)
• Double-Blind Method
• Female
• Humans
• Male
• Middle Aged
• Parkinson Disease, Secondary (chemically induced, drug therapy)
• Schizophrenia (drug therapy)
• Trihexyphenidyl (therapeutic use)