Cutaneous leukocytoclastic vasculitis with cervical tuberculous lymphadenitis: a case report and literature review.

Abstract

Cutaneous leukocytoclastic vasculitis (CLV) is a small-vessel vasculitis localized to the skin. Many possible causes exist for this pathological condition, including drugs, infection, collagen vascular disease, and malignancy. However, Mycobacterium tuberculosis is rarely reported to be associated with CLV. Here, we report a 49-year-old male patient that presented with fever, myalgia, and multiple palpable purpura on both of his legs. The biopsy from the purpura yielded a histologic diagnosis of leukocytoclastic vasculitis. The patient had several enlarged lymph nodes on his right neck, and the biopsy revealed tuberculous lymphadenitis. There were no signs of vasculitis present in the internal organs. After anti-tuberculosis treatment, his fever declined and the skin purpura were completely resolved. Although incidence is rare, tuberculosis should be considered as a possible cause of CLV.

• Authors: Hee Man Kim, Yong-Beom Park, Ho Young Maeng, Soo-Kon Lee
• Journal: Rheumatology international (Rheumatol Int) Vol. 26 Issue 12 Pg. 1154-7 (Oct 2006) ISSN: 0172-8172 [Print] Germany
• PMID: 16830160 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Antitubercular Agents

Topics

• Adolescent
• Adult
• Antitubercular Agents (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Skin (pathology)
• Skin Diseases, Vascular (diagnosis, drug therapy, microbiology)
• Treatment Outcome
• Tuberculosis, Lymph Node (complications, drug therapy, pathology)
• Vasculitis, Leukocytoclastic, Cutaneous (diagnosis, drug therapy, microbiology)