[Arterial blood gases study in patients with stable chronic obstructive pulmonary disease in accordance with spirometric values]

• Abstract: BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate the need to assess arterial blood gases in patients with stable chronic obstructive pulmonary disease (COPD) in accordance with spirometric values. PATIENTS AND METHOD: Transverse study in stable COPD patients with spirometry and pulse oximetry assessment. Specific exclusion criteria were: diagnosis of asthma, sleep apnea syndrome or respiratory failure not due to COPD. Diagnostic of respiratory failure was established when pulse oximetry saturation was < or = 92%; we evaluated the best predicted FEV1 cut-off value. RESULTS: 467 patients (age = 64 [8] yr) were evaluated. FEV1 was 44 (14) % predicted. Two patients (1.5%) with FEV1 > 50 % and 29 patients (23.6%) with FEV1 between 41 and 50% had respiratory failure. Sensitivity (0.98) and rate of false-negative (0.98) at a cut-off of 50% predicted value FEV1 was superior to sensitivity (0.75%) and rate of false-negative (0.87) at a cut-off of 40% predicted value FEV1. CONCLUSIONS: In stable COPD patients, the rate of respiratory failure increases when the predicted value FEV1 is below 50%. Therefore, we recommend this spirometric cut-off to evaluate arterial blood gases.
• Authors: José Fernández Guerra, José María García Jiménez, Emilio Perea-Milla López, José Joaquín Cebrián Gallardo, Elena Mora Ruiz, Luis Felipe Moreno Arrastio (Affiliation: Unidad de Neumología, Hospital Costa del Sol, Marbella, Málaga, España. jfguerra at hcs.es)
• Journal: Medicina clínica (Med Clin (Barc)) Vol. 127 Issue 3 Pg. 90-2 (Jun 17 2006) ISSN: 0025-7753 [Print] Spain
• Vernacular Title: Gasometría arterial en pacientes con enfermedad pulmonar obstructiva crónica estable según los valores de la espirometría.
• PMID: 16827998 (Publication Type: English Abstract, Journal Article)

Topics

• Aged
• Female
• Forced Expiratory Volume
• Humans
• Male
• Middle Aged
• Oximetry
• Predictive Value of Tests
• Pulmonary Disease, Chronic Obstructive (blood, physiopathology)
• Spirometry