Abstract | OBJECTIVE: METHODS: RESULTS: Compared to active coal miners without CWP (8.23 microg/mL), TNF-alpha concentration was gradually decreased when dust exposure was stopped (5.90 microg/mL). Elevated surfactant protein A (SP-A) level and phosphatidylglycerol (PG) to phosphatidylinositol (PI) ratio were found in miners actively exposed to coal dust (6528 ng/mL for SP-A and 10. for PG/PI), and both parameters decreased when CWP progressed from CWP (0/1) (3419 microg/mL for SP-A and 5.9 for PG/PI) to CWP (1/1) (1654 microg/mL for SP-A and 5.5 for PG/PI). CONCLUSION:
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Authors | Jing-Cai Xing, Wei-Hong Chen, Wen-Hui Han, Mei-Feng Guo, Steffeni Rehn, Joachim Bruch |
Journal | Biomedical and environmental sciences : BES
(Biomed Environ Sci)
Vol. 19
Issue 2
Pg. 124-9
(Apr 2006)
ISSN: 0895-3988 [Print] China |
PMID | 16827183
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers
- Phospholipids
- Pulmonary Surfactant-Associated Protein A
- Tumor Necrosis Factor-alpha
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Topics |
- Adult
- Animals
- Biomarkers
(analysis)
- Bronchoalveolar Lavage Fluid
(chemistry)
- Coal Mining
- Disease Progression
- Humans
- L Cells
- Mice
- Middle Aged
- Phospholipids
(metabolism)
- Pneumoconiosis
(diagnosis, metabolism, physiopathology)
- Pulmonary Surfactant-Associated Protein A
(metabolism)
- Tumor Necrosis Factor-alpha
(metabolism)
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