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Healing of intrabony peri-implantitis defects following application of a nanocrystalline hydroxyapatite (Ostim) or a bovine-derived xenograft (Bio-Oss) in combination with a collagen membrane (Bio-Gide). A case series.

AbstractOBJECTIVES:
The aim of the present case series was to evaluate the healing of intrabony peri-implantitis defects following application of a nanocrystalline hydroxyapatite (NHA) or a bovine-derived xenograft in combination with a collagen membrane (BDX+BG).
MATERIAL AND METHODS:
Twenty-two patients having moderate peri-implantitis (n=22 intrabony defects) were randomly treated with (i) access flap surgery (AFS) and the application of NHA, or with AFS and the application of BDX+BG. Clinical parameters were recorded at baseline and after 6 months of non-submerged healing.
RESULTS:
Post-operative wound healing revealed that NHA compromized initial adhesion of the mucoperiosteal flaps in all patients. At 6 months after therapy, NHA showed a reduction in the mean PD from 7.0+/-0.6 to 4.9+/-0.6 mm and a change in the mean clinical attachment loss (CAL) from 7.5+/-0.8 to 5.7+/-1.0 mm. In the BDX+BC group, the mean PD was reduced from 7.1+/-0.8 to 4.5+/-0.7 mm and the mean CAL changed from 7.5+/-1.0 to 5.2+/-0.8 mm.
CONCLUSION:
Within the limits of the present case series, it can be concluded that at 6 months after surgery both therapies resulted in clinically important PD reductions and CAL gains.
AuthorsF Schwarz, K Bieling, T Latz, E Nuesry, J Becker
JournalJournal of clinical periodontology (J Clin Periodontol) Vol. 33 Issue 7 Pg. 491-9 (Jul 2006) ISSN: 0303-6979 [Print] United States
PMID16820037 (Publication Type: Journal Article, Randomized Controlled Trial)
Chemical References
  • Bio-Gide
  • Bio-Oss
  • Biocompatible Materials
  • Bone Substitutes
  • Dental Implants
  • Membranes, Artificial
  • Minerals
  • Collagen
  • Durapatite
Topics
  • Alveolar Bone Loss (etiology, surgery)
  • Animals
  • Biocompatible Materials
  • Bone Substitutes
  • Cattle
  • Collagen
  • Dental Implantation, Endosseous (adverse effects)
  • Dental Implants (adverse effects)
  • Durapatite
  • Female
  • Guided Tissue Regeneration, Periodontal (methods)
  • Humans
  • Male
  • Membranes, Artificial
  • Middle Aged
  • Minerals
  • Periodontal Index
  • Periodontitis (etiology, surgery)
  • Single-Blind Method
  • Treatment Outcome

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