Pylorus-preserving pancreatoduodenectomy. Experience in 20 patients.

Abstract

Twenty patients underwent a pylorus-preserving pancreatoduodenectomy for benign or malignant periampullary and pancreatic disease. Eighteen patients had a partial and two patients a total pancreatectomy. There were 19 elective and 1 emergency operations. Post-operative mortality was 4% (1/20 patients) and the median follow up was 31 months (range, 15-75 months), during which period 8 patients with a malignant disease died. Pylorus-preserving pancreatoduodenectomy did not compromise survival in ampullary cancer. One patient developed a marginal ulcer during the study period and one of twelve patients, examined by technetium scintigraphy (done more than 3 months after the procedure), had delayed gastric emptying. Two patients presented with a gastric retention as the first sign of recurrent pancreatic cancer. The result of the operation was judged as excellent in 7 patients, good in 8 and as bad in only 2 of the 17 patients who survived more than 6 months. Body weight was studied in 15 patients surviving more than one year after operation; five patients had gained weight, two had lost weight and in 8 there was no difference. Pylorus-preserving pancreatoduodenectomy seems to be a valuable alternative in the treatment of patients with benign and selected malignant pancreaticobiliary disease.

• Authors: J Lerut, P J Luder, L Krähenbühl, P H Gertsch, L H Blumgart
• Journal: HPB surgery : a world journal of hepatic, pancreatic and biliary surgery (HPB Surg) Vol. 4 Issue 2 Pg. 109-17; discussion 117-9 (Jun 1991) ISSN: 0894-8569 [Print] United States
• PMID: 1681888 (Publication Type: Journal Article)

Topics

• Adult
• Aged
• Bile Duct Neoplasms (surgery)
• Female
• Gastric Emptying (physiology)
• Humans
• Male
• Middle Aged
• Pancreatic Neoplasms (surgery)
• Pancreaticoduodenectomy (adverse effects, methods)
• Pancreatitis (surgery)
• Peptic Ulcer (etiology)
• Postoperative Period
• Pylorus