Abstract | OBJECTIVE: METHODS: RESULTS: 71 patients were included. There were two (5.2%) blood cultures positive in group A and three (9%) in group B. Organisms isolated were S. pneumoniae (n=3) and H. influenzae-b (n=2). There was only one treatment failure in each of the groups. One was due to penicillin resistant H. influenzae -b and the other was due to worsening of pneumonia. The mean time taken for normalization of tachypnea, hypoxia, chest wall indrawing and inability to feed was similar (P-N.S). Mean duration of IV therapy in group A was 76+/-25 hrs and group B was 75+/-24 hrs (p>0.1). CONCLUSION: In children of 2-59 months, sequential injectable C. pen and gentamicin combination, followed by oral amoxicillin or sequential IV and oral amox-clav were equally effective for the treatment of severe or very severe hypoxemic community acquired pneumonia.
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Authors | Arun Bansal, Sunit C Singhi, M Jayashree |
Journal | Indian journal of pediatrics
(Indian J Pediatr)
Vol. 73
Issue 4
Pg. 305-9
(Apr 2006)
ISSN: 0973-7693 [Electronic] India |
PMID | 16816491
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Bacterial Agents
- Gentamicins
- Penicillins
- Amoxicillin-Potassium Clavulanate Combination
- Amoxicillin
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Topics |
- Administration, Oral
- Amoxicillin
(administration & dosage, therapeutic use)
- Amoxicillin-Potassium Clavulanate Combination
(therapeutic use)
- Anti-Bacterial Agents
(therapeutic use)
- Child, Preschool
- Drug Therapy, Combination
- Female
- Gentamicins
(therapeutic use)
- Haemophilus Infections
(drug therapy)
- Haemophilus influenzae
- Humans
- Infant
- Infusions, Intravenous
- Male
- Penicillins
(therapeutic use)
- Pneumonia, Bacterial
(drug therapy)
- Pneumonia, Pneumococcal
(drug therapy)
- Treatment Outcome
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