Stevens-Johnson syndrome associated with glipizide therapy.

Abstract

We describe a patient with Stevens-Johnson syndrome (erythema multiforme major) associated with an increase in glipizide dosage administration. Glipizide is a second-generation sulfonylurea commonly used to treat patients with noninsulin-dependent diabetes mellitus. Although several reports have documented Stevens-Johnson syndrome caused by first-generation sulfonylureas, our case appears to be the first report of a second-generation sulfonylurea associated with Stevens-Johnson syndrome.

• Authors: Jeffrey B Cheng, Robert C Anderson, Ponciano D Cruz Jr
• Journal: Dermatitis : contact, atopic, occupational, drug (Dermatitis) Vol. 17 Issue 1 Pg. 36-8 (Mar 2006) ISSN: 1710-3568 [Print] United States
• PMID: 16800277 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glipizide

Topics

• Adult
• Biopsy, Needle
• Diabetes Mellitus, Type 2 (diagnosis, drug therapy)
• Follow-Up Studies
• Glipizide (adverse effects, therapeutic use)
• Humans
• Immunohistochemistry
• Male
• Rare Diseases
• Severity of Illness Index
• Stevens-Johnson Syndrome (chemically induced, pathology)