Abstract | BACKGROUND: OBJECTIVE: METHOD: RESULTS: The patient developed strong urticarial reactions during open tests with both powdered chalks and had milder reactions to the open test with CMC 10% aqueous (aq) and to prick testing with CMC 0.1% aq. No reaction to MHEC or any of the other ingredients of the chalks was observed. No relevant delayed reaction was noted. CONCLUSION: CMC can cause contact urticaria. It remains unclear why our patient reacted more strongly to the chalk than to CMC itself. We speculate that the abrasive nature of the chalk enhances the cutaneous penetration of CMC or that calcium carbonate, the main ingredient of the chalk, acts as an adjuvant. It is also possible that CMC and MHEC cross-react and that our negative results with MHEC may be due to improper testing technique or concentrations.
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Authors | Linda Moreau, Ghanima Alomer, Normand Dubé, Denis Sasseville |
Journal | Dermatitis : contact, atopic, occupational, drug
(Dermatitis)
Vol. 17
Issue 1
Pg. 29-31
(Mar 2006)
ISSN: 1710-3568 [Print] United States |
PMID | 16800275
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Calcium Carbonate
- Carboxymethylcellulose Sodium
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Topics |
- Adolescent
- Calcium Carbonate
(adverse effects)
- Carboxymethylcellulose Sodium
(adverse effects)
- Cross Reactions
- Dermatitis, Allergic Contact
(diagnosis, etiology)
- Female
- Follow-Up Studies
- Humans
- Hypersensitivity, Immediate
(diagnosis, etiology)
- Patch Tests
- Risk Assessment
- Severity of Illness Index
- Urticaria
(diagnosis, etiology)
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