Onset of severe refractory thrombocytopenia following surgery in a patient with type 2B von Willebrand disease--a case report.

Abstract

A case of a severe thrombocytopenia occurring in a patient with type 2B von Willebrand disease following an esophagectomy is described. As platelet transfusions were ineffective due to alloimunization, effective hemostasis was achieved only with the factor VIII/von Willebrand factor concentrate Haemate P.

• Authors: Massimo Franchini
• Journal: Hematology (Amsterdam, Netherlands) (Hematology) Vol. 11 Issue 2 Pg. 127-9 (Apr 2006) ISSN: 1024-5332 [Print] England
• PMID: 16753854 (Publication Type: Case Reports, Journal Article)

Chemical References

• HLA Antigens
• Isoantibodies
• Factor VIII

Topics

• Carcinoma, Squamous Cell (complications, surgery)
• Esophageal Neoplasms (complications, surgery)
• Factor VIII (administration & dosage)
• Female
• HLA Antigens (immunology)
• Hemorrhage (etiology, prevention & control)
• Humans
• Isoantibodies (immunology)
• Middle Aged
• Postoperative Complications (immunology)
• Thrombocytopenia (drug therapy, immunology)
• von Willebrand Diseases (complications, drug therapy)