TFIIIC boxes in the genome.

Abstract

In this issue of Cell, Noma et al. (2006) show that B-boxes and TFIIIC limit the spread of heterochromatin at the silent mat region in the fission yeast genome. Global analysis of TFIIIC distribution revealed dispersed sites of association that coalesce at the nuclear periphery, suggesting that TFIIIC may act as a barrier throughout the genome.

• Authors: Lori L Wallrath, Pamela K Geyer
• Journal: Cell (Cell) Vol. 125 Issue 5 Pg. 829-31 (Jun 02 2006) ISSN: 0092-8674 [Print] United States
• PMID: 16751090 (Publication Type: Journal Article, Review, Comment)

Chemical References

• DNA-Binding Proteins
• Heterochromatin
• Transcription Factors, TFIII
• transcription factor TFIIIC
• DNA Polymerase III

Topics

• Binding Sites (genetics)
• Cell Nucleus (genetics)
• DNA Polymerase III (genetics)
• DNA-Binding Proteins (genetics)
• Gene Expression Regulation, Fungal (genetics)
• Genome, Fungal (genetics)
• Heterochromatin (genetics)
• Schizosaccharomyces (genetics, metabolism)
• Transcription Factors, TFIII (genetics)
• Transcription, Genetic (genetics)