Abstract | OBJECTIVE: To evaluate how functional disability impacts on health related quality of life (HRQOL) of patients with extremity soft tissue sarcoma (STS) at 1 year post-surgery. DESIGN AND SETTING: Survey of extremity STS patients pre-surgery and one-year post-treatment. PARTICIPANTS: 100 participants who were treated for extremity STS between 2001 and 2003 at four Canadian hospitals. Patients were over 16 years, non-metastatic at diagnosis, and had limb salvage surgery. OUTCOME MEASURES: Musculoskeletal Tumor Society Rating Scale (MSTS), a measure of impairment; Toronto Extremity Salvage Score (TESS), a measure of activity limitations; Reintegration to Normal Living Index (RNL), a measure of participation restrictions; and EQ- VAS, a measure of HRQOL. RESULTS: After adjusting for demographic and clinical variables, impairment explained 54%, activity limitations explained 48%, and participation restrictions explained 61% of the variation in HRQOL. After adjustment, when all three functional measures were included in the model, only participation restrictions had a significant impact on HRQOL explaining 63% of the variation. CONCLUSION: Impairment and activity limitations affect the daily activities a patient can perform, but it is the restriction in participation of life roles and situations that has the greatest effect on patient's HRQOL.
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Authors | Daphne Schreiber, Robert S Bell, Jay S Wunder, Brian O'Sullivan, Robert Turcotte, Bassam A Masri, Aileen M Davis |
Journal | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
(Qual Life Res)
Vol. 15
Issue 9
Pg. 1439-46
(Nov 2006)
ISSN: 0962-9343 [Print] Netherlands |
PMID | 16732468
(Publication Type: Journal Article)
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Topics |
- Activities of Daily Living
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Canada
- Databases, Factual
- Disability Evaluation
- Female
- Humans
- Linear Models
- Male
- Middle Aged
- Multicenter Studies as Topic
- Postoperative Period
- Quality of Life
- Sarcoma
(classification, psychology, surgery)
- Severity of Illness Index
- Surveys and Questionnaires
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