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Evaluating function and health related quality of life in patients treated for extremity soft tissue sarcoma.

AbstractOBJECTIVE:
To evaluate how functional disability impacts on health related quality of life (HRQOL) of patients with extremity soft tissue sarcoma (STS) at 1 year post-surgery.
DESIGN AND SETTING:
Survey of extremity STS patients pre-surgery and one-year post-treatment.
PARTICIPANTS:
100 participants who were treated for extremity STS between 2001 and 2003 at four Canadian hospitals. Patients were over 16 years, non-metastatic at diagnosis, and had limb salvage surgery.
OUTCOME MEASURES:
Musculoskeletal Tumor Society Rating Scale (MSTS), a measure of impairment; Toronto Extremity Salvage Score (TESS), a measure of activity limitations; Reintegration to Normal Living Index (RNL), a measure of participation restrictions; and EQ-VAS, a measure of HRQOL.
RESULTS:
After adjusting for demographic and clinical variables, impairment explained 54%, activity limitations explained 48%, and participation restrictions explained 61% of the variation in HRQOL. After adjustment, when all three functional measures were included in the model, only participation restrictions had a significant impact on HRQOL explaining 63% of the variation.
CONCLUSION:
Impairment and activity limitations affect the daily activities a patient can perform, but it is the restriction in participation of life roles and situations that has the greatest effect on patient's HRQOL.
AuthorsDaphne Schreiber, Robert S Bell, Jay S Wunder, Brian O'Sullivan, Robert Turcotte, Bassam A Masri, Aileen M Davis
JournalQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (Qual Life Res) Vol. 15 Issue 9 Pg. 1439-46 (Nov 2006) ISSN: 0962-9343 [Print] Netherlands
PMID16732468 (Publication Type: Journal Article)
Topics
  • Activities of Daily Living
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Canada
  • Databases, Factual
  • Disability Evaluation
  • Female
  • Humans
  • Linear Models
  • Male
  • Middle Aged
  • Multicenter Studies as Topic
  • Postoperative Period
  • Quality of Life
  • Sarcoma (classification, psychology, surgery)
  • Severity of Illness Index
  • Surveys and Questionnaires

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