Abstract | OBJECTIVES: The objectives of this study were to elucidate the clinical manifestations of Aeromonas infections and the association of putative virulence genes with clinical invasiveness. METHODS: 116 consecutive clinical Aeromonas isolates collected from July 1999 to June 2001 in a medical center in southern Taiwan were included. All isolates were identified by biochemical phenotyping and their genomic sequences encoding eight putative virulence factors, including cytolytic enterotoxin ( AHCYTOEN), aerolysin (aerA), hemolysin (hlyA), heat-labile enterotoxin (alt), heat-stable enterotoxin (ast), and components of type III secretion system (ascV, aexT and ascF-ascG) were analyzed using polymerase chain reaction and colony blot hybridization. The association of clinical diseases of the patients with the putative virulence genes in the isolates was analyzed. RESULTS: CONCLUSIONS:
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Authors | Chi-Jung Wu, Jiunn-Jong Wu, Jing-Jou Yan, Hsin-Chun Lee, Nan-Yao Lee, Chia-Ming Chang, Hsin-I Shih, Hsiu-Mei Wu, Li-Rong Wang, Wen-Chien Ko |
Journal | The Journal of infection
(J Infect)
Vol. 54
Issue 2
Pg. 151-8
(Feb 2007)
ISSN: 1532-2742 [Electronic] England |
PMID | 16716402
(Publication Type: Journal Article)
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Chemical References |
- Bacterial Proteins
- Virulence Factors
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Topics |
- Aeromonas
(classification, genetics, isolation & purification, pathogenicity)
- Bacteremia
(microbiology, physiopathology)
- Bacterial Proteins
(genetics, metabolism)
- Biliary Tract Diseases
(microbiology, physiopathology)
- Gram-Negative Bacterial Infections
(epidemiology, microbiology, physiopathology)
- Hospitals, University
- Humans
- Liver Diseases
(microbiology, physiopathology)
- Soft Tissue Infections
(microbiology, physiopathology)
- Taiwan
(epidemiology)
- Virulence Factors
(genetics, metabolism)
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