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In juvenile idiopathic arthritis, is folate supplementation effective against methotrexate toxicity at the expense of methotrexate's efficacy?

AuthorsO G Killeen, J M Gardner-Medwin (Affiliation: Paediatric Rheumatology, Department of Child Health, RHSC, Glasgow, UK. orlakilleen at doctors.org.uk)
JournalArchives of disease in childhood (Arch Dis Child) Vol. 91 Issue 6 Pg. 537-8 (Jun 2006) ISSN: 1468-2044 England
PMID16714734 (Publication Type: Journal Article, Review)
Chemical References
  • Antirheumatic Agents
  • Folic Acid Antagonists
  • Methotrexate
  • Folic Acid
Topics
  • Antirheumatic Agents (adverse effects, therapeutic use)
  • Arthritis, Juvenile Rheumatoid (drug therapy)
  • Child
  • Dietary Supplements
  • Female
  • Folic Acid (administration & dosage)
  • Folic Acid Antagonists (adverse effects, therapeutic use)
  • Humans
  • Methotrexate (adverse effects, therapeutic use)