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Mechanisms of fluoroquinolone and macrolide resistance in Campylobacter spp.

Abstract
The incidence of human Campylobacter infections is increasing worldwide, as well as the proportion of isolates resistant to fluoroquinolones and/or macrolides, the drugs of choice to treat campylobacteriosis. In this review, we report recent developments in the understanding of the resistance mechanisms to fluoroquinolones and macrolides. In addition, we will discuss the recent findings on multidrug resistance in Campylobacter spp.
AuthorsSophie Payot, Jean-Michel Bolla, Deborah Corcoran, Séamus Fanning, Francis Mégraud, Qijing Zhang
JournalMicrobes and infection (Microbes Infect) Vol. 8 Issue 7 Pg. 1967-71 (Jun 2006) ISSN: 1286-4579 [Print] France
PMID16713726 (Publication Type: Journal Article, Review)
Chemical References
  • Anti-Bacterial Agents
  • Fluoroquinolones
  • Macrolides
Topics
  • Anti-Bacterial Agents (pharmacology)
  • Campylobacter (drug effects, genetics)
  • Campylobacter Infections (microbiology)
  • Drug Resistance, Bacterial (genetics)
  • Drug Resistance, Multiple, Bacterial
  • Fluoroquinolones (pharmacology)
  • Humans
  • Macrolides (pharmacology)

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