Postoperative radiotherapy with high dose rate iridium 192 mould for prevention of earlobe keloids.

Abstract

BACKGROUND:

A 50% to 80% recurrence rate of earlobe keloids can occur following a simple excision. Many modalities, including radiotherapy, have been suggested to reduce the postoperation recurrence.

OBJECTIVE:

The aim of the present study was to determine the efficacy of postoperative radiotherapy by a high dose rate Iridium 192 mould in the prevention of earlobe keloids recurrence.

MATERIAL AND METHOD:

Between March 1999 and March 2003, 22 patients with 24 earlobe keloids were treated by radiotherapy immediately following surgical excision. A dose of 15 Gray in 3 fractions was delivered at a point placed 5 mm from the axis of the Iridium sources.

RESULTS:

From the 22 patients with 24 keloids who were treated, 15 patients with 16 keloids were followed for a minimum of 6 months. Recurrence occurred in two keloids (12.5%). There were no severe adverse effects.

CONCLUSION:

Postoperative radiotherapy by high dose rate Iridium 192 mould was an effective prevention of earlobe keloids recurrence. It was well tolerated and did not present any significant side effects.

• Authors: Ladawan Narkwong, Poth Thirakhupt
• Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet (J Med Assoc Thai) Vol. 89 Issue 4 Pg. 428-33 (Apr 2006) ISSN: 0125-2208 [Print] Thailand
• PMID: 16696385 (Publication Type: Journal Article)

Chemical References

• Iridium Radioisotopes
• Radiopharmaceuticals

Topics

• Adolescent
• Adult
• Ear, External (pathology, radiation effects)
• Female
• Humans
• Iridium Radioisotopes (therapeutic use)
• Keloid (radiotherapy, surgery)
• Male
• Postoperative Period
• Prospective Studies
• Radiopharmaceuticals (therapeutic use)
• Radiotherapy, Adjuvant
• Secondary Prevention