Central diabetes insipidus in a patient with malaria tropica.

Up to 21% of severe cases of malaria tropica are associated with polyuria and are life-threatening. We describe a 39-yr-old man with malaria tropica who developed disseminated intravascular coagulation, polyuria, and a pituitary lesion. Empiric treatment with vasopressin improved the polyuria. This is the first case of malaria tropica in which central diabetes insipidus has been documented.
AuthorsS Schubert, H Achenbach, L Engelmann, G Borte, M Stumvoll, C A Koch
JournalJournal of endocrinological investigation (J Endocrinol Invest) Vol. 29 Issue 3 Pg. 265-6 (Mar 2006) ISSN: 0391-4097 [Print] Italy
PMID16682843 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Vasopressins
  • Hydrocortisone
  • Adrenal Insufficiency (complications, diagnosis, drug therapy)
  • Adult
  • Diabetes Insipidus, Neurogenic (complications, diagnosis, therapy)
  • Disseminated Intravascular Coagulation (etiology, therapy)
  • Humans
  • Hydrocortisone (administration & dosage)
  • Magnetic Resonance Imaging
  • Malaria, Falciparum (complications, drug therapy)
  • Male
  • Natriuresis
  • Pituitary Gland, Posterior (pathology)
  • Polyuria
  • Pulmonary Embolism (etiology, therapy)
  • Renal Insufficiency (etiology, therapy)
  • Vasopressins (administration & dosage)

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