Central diabetes insipidus in a patient with malaria tropica.

Abstract

Up to 21% of severe cases of malaria tropica are associated with polyuria and are life-threatening. We describe a 39-yr-old man with malaria tropica who developed disseminated intravascular coagulation, polyuria, and a pituitary lesion. Empiric treatment with vasopressin improved the polyuria. This is the first case of malaria tropica in which central diabetes insipidus has been documented.

• Authors: S Schubert, H Achenbach, L Engelmann, G Borte, M Stumvoll, C A Koch
• Journal: Journal of endocrinological investigation (J Endocrinol Invest) Vol. 29 Issue 3 Pg. 265-6 (Mar 2006) ISSN: 0391-4097 [Print] Italy
• PMID: 16682843 (Publication Type: Case Reports, Journal Article)

Chemical References

• Vasopressins
• Hydrocortisone

Topics

• Adrenal Insufficiency (complications, diagnosis, drug therapy)
• Adult
• Diabetes Insipidus, Neurogenic (complications, diagnosis, therapy)
• Disseminated Intravascular Coagulation (etiology, therapy)
• Humans
• Hydrocortisone (administration & dosage)
• Magnetic Resonance Imaging
• Malaria, Falciparum (complications, drug therapy)
• Male
• Natriuresis
• Pituitary Gland, Posterior (pathology)
• Polyuria
• Pulmonary Embolism (etiology, therapy)
• Renal Insufficiency (etiology, therapy)
• Vasopressins (administration & dosage)