Successful steroid treatment of acquired idiopathic partial hypohidrosis.

Abstract

The pathogenesis of idiopathic-acquired hypohidrosis remains unknown, and no specific causes have yet been established. We report a 34-year-old man with acquired idiopathic hypohidrosis successfully treated with prednisolone. The patient noticed heat intolerance and hypohidrosis of the pectoral and back during the summer. No systemic disease or neurological findings were identified. Eccrine sweat glands displayed infiltration by inflammatory cells, with immunoglobulin G and C3 deposition in the basement membrane. Steroid therapy improved the hypohidrosis. An immunological pathogenesis could be a major factor in idiopathic-acquired hypohidrosis.

• Authors: Asako Yoritaka, Tsunekazu Hishima, Kumiko Akagi, Shuji Kishida
• Journal: The Journal of dermatology (J Dermatol) Vol. 33 Issue 4 Pg. 265-7 (Apr 2006) ISSN: 0385-2407 [Print] England
• PMID: 16674791 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Prednisolone

Topics

• Adult
• Glucocorticoids (therapeutic use)
• Humans
• Hypohidrosis (drug therapy, pathology)
• Male
• Prednisolone (therapeutic use)