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Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation.

Abstract
We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.
AuthorsErika Driver-Dunckley, Virgilio Gerald H Evidente, Charles H Adler, Renee Hillman, Jose Hernandez, Geoffrey Fletcher, Mark K Lyons
JournalMovement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 21 Issue 8 Pg. 1287-9 (Aug 2006) ISSN: 0885-3185 [Print] United States
PMID16671093 (Publication Type: Journal Article)
Copyright(c) 2006 Movement Disorder Society
Chemical References
  • Antiparkinson Agents
  • Levodopa
Topics
  • Aged
  • Antiparkinson Agents (therapeutic use)
  • Deep Brain Stimulation
  • Female
  • Humans
  • Levodopa (therapeutic use)
  • Male
  • Middle Aged
  • Parkinson Disease (drug therapy, therapy)
  • Restless Legs Syndrome (etiology, therapy)
  • Thalamus

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