[The organization of the microcirculatory bed of the vascular plexus of the lateral cerebral ventricles in rabbits].

Abstract

Electron microscopic studies of the choroid plexus' microvessels in the rabbit brain revealed diaphragm-covered caveolae and fenestrae in them. Some endotheliocytes possess outgrowths and sprouts on the abluminal surface that penetrate through the basal membrane of the capillaries into the brain and make contacts with its neurosecretory cells. The choroid capillaries were shown to be innervated by nerve fibers and terminals adjoining the basal membrane of the endothelium. Fever induced by i.v. pyrogenal was accompanied by changes in the organisation and permeability of the capillaries. These changes seem to be due to the action of interleukin-I released from activated blood and endothelial cells under the influence of pyrogenal.

• Authors: V N Gurin, L I Archakova
• Journal: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova (Fiziol Zh SSSR Im I M Sechenova) Vol. 77 Issue 9 Pg. 150-8 (Sep 1991) ISSN: 0015-329X [Print] Russia (Federation)
• Vernacular Title: Organizatsiia mikrotsirkuliatornogo rusla sosudistogo spleteniia bokovykh zheludochkov mozga krolikov.
• PMID: 1666597 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Lipopolysaccharides
• Pyrogens
• pyrogenal

Topics

• Animals
• Choroid Plexus (blood supply, ultrastructure)
• Fever (chemically induced, pathology)
• Lipopolysaccharides
• Microcirculation (ultrastructure)
• Microscopy, Electron
• Pyrogens
• Rabbits