[Mechanisms of the therapeutic effect of bemitil in neuromuscular diseases].

Abstract

Studies into the mechanism of the therapeutic action of bemitil were carried out in 21 patients with neuromuscular diseases. Measurements of lipid peroxidation and permeability of the erythrocytic membranes demonstrated the drug to influence carbohydrate and lipid metabolism, lipid peroxidation, and permeability of the cellular membranes. It is recommended that bemitil be used for the treatment of neuromuscular diseases.

• Authors: V S Lobzin, L A Saĭkova, M L Chukhlovina, V G Pustozerov
• Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) (Zh Nevropatol Psikhiatr Im S S Korsakova) Vol. 91 Issue 9 Pg. 22-4 ( 1991) ISSN: 0044-4588 [Print] Russia (Federation)
• Vernacular Title: K mekhanizmam terapevticheskogo deĭstviia bemitila pri nervno-myshechnykh zabolevaniiakh.
• PMID: 1664607 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Antioxidants
• Benzimidazoles
• bemethyl

Topics

• Adolescent
• Adult
• Antioxidants (therapeutic use)
• Benzimidazoles (therapeutic use)
• Erythrocytes (drug effects, metabolism)
• Female
• Humans
• Lipid Peroxidation (drug effects, physiology)
• Male
• Middle Aged
• Muscular Dystrophies (blood, drug therapy, etiology)
• Myotonic Dystrophy (blood, drug therapy, etiology)