[A case of severe glaucoma with pseudopemphigoid successfully treated by filtration surgery using amniotic membrane].

Abstract

BACKGROUND:

It is necessary to decrease topical anti-glaucoma medication for severe glaucoma with pseudopemphigoid caused by anti-glaucoma eye drops. Glaucoma filtrating surgery is often needed instead of medication, but the prognosis is poor because it induces scar fomation and makes the filtrating bleb vanish.

CASE:

An 85-year-old male patient with exfoliation syndrome had twice undergone glaucoma surgery about ten years previously. His intra-ocular pressure (IOP) was high despite topical anti-glaucoma medication. At the first examination in our hospital, he had severe superficial punctate keratopathy, blephariticshortening and symblepharon, and we therefore diagnosed severe pseudopemphigoid induced by anti-glaucoma eye drops. Because his IOP could not be controlled by topical and general medication, we conducted a glaucoma filtrating operation using amniotic membrane.

CONCLUSION:

The administration of oral anti-inflammatory drugs before and after surgery and the use of amniotic membrane prevented post-operative scar formation and the progress of symblepharon, resulting in the successful control of IOP after surgery.

• Authors: Keiko Hino, Kazuhiko Mori, Chie Sotozono, Yoko Ikeda, Shigeta Naruse, Takeshi Ishibashi, Yukako Nanjo, Shigeru Kinoshita
• Journal: Nippon Ganka Gakkai zasshi (Nippon Ganka Gakkai Zasshi) Vol. 110 Issue 4 Pg. 312-7 (Apr 2006) ISSN: 0029-0203 [Print] Japan
• PMID: 16642950 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Pilocarpine
• Carteolol

Topics

• Aged, 80 and over
• Amnion
• Carteolol (adverse effects, therapeutic use)
• Filtering Surgery
• Glaucoma (drug therapy, surgery)
• Humans
• Male
• Pemphigoid, Bullous (chemically induced)
• Pilocarpine (adverse effects, therapeutic use)
• Postoperative Complications