Evaluation of substituted oxime ethers for growth regulatory activity against Spodoptera litura (F.).

Abstract

Insect growth regulatory activity (IGR) of fifty-two substituted oxime ethers were evaluated against an important polyphagous lepidopteran crop pest, Spodoptera litura (F.). A number of compounds produced symptoms comparable to exogenously applied juvenile hormone. Maximum IGR activity was exhibited by 4'-(2,6,6-trimethyl-2-cyclohexen- -yl)-3'-buten-2'(E)-ketoxime-N-O-alkyl ether with an ED50 (morphological) of 40 microg g(-1) body weight, compared to 20 microg g(-1) of JH III. Two more compounds namely 4'-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3'-buten-2'(Z)-ketoxime-N-O-methyl propyl ether (ED50 192 microg g(-1)) and 4'-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3'-buten-2'(E)-ketoxime-N-O-pentyl ether (ED50 380 microg g(-1)) showed considerable IGR activity, whereas 4'-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3'-buten-2'(E)-ketoxime-N-O-pentyl ether was found to be toxic to the larvae (ED50 268 microg g(-1)). Three compounds used in this study were also synergised by piperonyl butoxide (PBO). The synergistic ratios were found in the range of 1.33 to 4.605. The ovicidal activity of the oxime ethers is not significant.

• Authors: H Izadi, B Subrahmanyam
• Journal: Communications in agricultural and applied biological sciences (Commun Agric Appl Biol Sci) Vol. 70 Issue 4 Pg. 651-60 ( 2005) ISSN: 1379-1176 [Print] Belgium
• PMID: 16628899 (Publication Type: Evaluation Study, Journal Article)

Chemical References

• Ethers
• Insecticides
• Juvenile Hormones
• Oximes
• Pesticide Synergists
• Piperonyl Butoxide

Topics

• Animals
• Biological Assay
• Dose-Response Relationship, Drug
• Ethers (chemical synthesis, pharmacology)
• Insecticides (pharmacology)
• Juvenile Hormones (pharmacology)
• Oximes (chemical synthesis, pharmacology)
• Pest Control, Biological (methods)
• Pesticide Synergists (pharmacology)
• Piperonyl Butoxide (pharmacology)
• Spodoptera (drug effects, growth & development)