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How we do it: surgery should be considered equally with I131 and thionamide treatment as first-line therapy for thyrotoxicosis.

AbstractRadioiodine and thionamide treatment are the most frequently used treatment modalities for thyrotoxicosis in Europe and North America with surgery being reserved for selected cases. * In our clinic patients were offered all three modalities via simultaneous interview with an endocrinologist and a surgeon, with international risk benefit data for radioiodine and thionamide therapy, and local risk benefit data for total thyroidectomy provided. * When given the choice, at least 15% of patients opted for total thyroidectomy over the other modalities. * In our series of 100 consecutive surgical patients there was a 4% malignancy rate. * Total thyroidectomy should be offered equally, with radioiodine and thionamide treatment, as a first line treatment modality in the management of thyrotoxicosis.
AuthorsR J A England, M B Kamath, A Jabreel, G Dunne, S L Atkin (Affiliation: Departments of Otolaryngology Head and Neck Surgery and Endocrinology, Hull Royal Infirmary, UK. rjaeathome at aol.com)
JournalClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (Clin Otolaryngol) Vol. 31 Issue 2 Pg. 160-2 (Apr 2006) ISSN: 1749-4478 England
PMID16620341 (Publication Type: Journal Article)
Chemical References
  • Antithyroid Agents
  • Iodine Radioisotopes
Topics
  • Adolescent
  • Adult
  • Aged
  • Antithyroid Agents (therapeutic use)
  • Female
  • Humans
  • Iodine Radioisotopes (therapeutic use)
  • Male
  • Middle Aged
  • Thyroidectomy
  • Thyrotoxicosis (surgery, therapy)
  • Treatment Outcome