Effect of potato on acid-base and mineral homeostasis in rats fed a high-sodium chloride diet.
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| Abstract |
Excessive dietary NaCl in association with a paucity of plant foods, major sources of K alkaline salts, is a common feature in Western eating habits which may lead to acid-base disorders and to Ca and Mg wasting. In this context, to evaluate the effects of potato, rich in potassium citrate, on acid-base homeostasis and mineral retention, Wistar rats were fed wheat starch (WS) or cooked potato (CP) diets with a low (0.5 %) or a high (2 %) NaCl content during 3 weeks. The replacement of WS by CP in the diets resulted in a significant urinary alkalinisation (pH from 5.5 to 7.3) parallel to a rise in citrate and K excretion. Urinary Ca and Mg elimination represented respectively 17 and 62 % of the daily absorbed mineral in rats fed the high-salt WS diet compared with 5 and 28 % in rats fed the high-salt CP diet. The total SCFA concentration in the caecum was 3-fold higher in rats fed the CP diets compared with rats fed the WS diets, and it led to a significant rise in Ca and Mg intestinal absorption (Ca from 39 to 56 %; Mg from 37 to 60 %). The present model of low-grade metabolic acidosis indicates that CP may be effective in alkalinising urine, enhancing citrate excretion and ameliorating Ca and Mg balance.
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| Authors | Agnès Narcy, Laetitia Robert, Andrzej Mazur, Christian Demigné, Christian Rémésy |
| Journal | The British journal of nutrition (Br J Nutr) Vol. 95 Issue 5 Pg. 925-32 (May 2006) ISSN: 0007-1145 [Print] England |
| PMID | 16611382 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't) |
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