Abstract | UNLABELLED: MATERIAL AND METHODS: RESULTS: The results showed that acceptor activity of rabbit liver tRNA for valine and arginine under 6, 12 and 24 h experimental myocardial ischemia in autumn was higher by 24-35% than in winter. Activities of rabbit liver valyl- and arginyl- tRNA synthetases under 6, 12 and 24 h experimental myocardial ischemia in autumn were lower by 15-32% than in winter. No differences in the activity of tRNA and aminoacyl- tRNA synthetases between control groups of both seasons were observed. CONCLUSIONS: The experimental data suggest that acceptor activity of rabbit liver tRNA for valine and arginine and activity of valyl- and arginyl- tRNA synthetases under 6, 12 and 24 h experimental myocardial ischemia are different in autumn and winter. The decrease of acceptor activity of tRNA for valine and arginine after experimental myocardial ischemia correlates with an increase in the activity of valyl- and arginyl- tRNA synthetases both in autumn and winter. It may be part of the compensatory mechanism of the cell to keep synthesis of protein in a normal range under extreme conditions.
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Authors | Hiliaras Rodovicius, Jūrate Burneckiene |
Journal | Medicina (Kaunas, Lithuania)
(Medicina (Kaunas))
Vol. 42
Issue 3
Pg. 225-30
( 2006)
ISSN: 1648-9144 [Electronic] Switzerland |
PMID | 16607065
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- RNA, Transfer
- Arginine
- Amino Acyl-tRNA Synthetases
- Valine
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Topics |
- Acute Disease
- Amino Acyl-tRNA Synthetases
(metabolism)
- Animals
- Arginine
(metabolism)
- Disease Models, Animal
- Liver
(enzymology, metabolism)
- Male
- Myocardial Ischemia
(enzymology, metabolism)
- Protein Biosynthesis
- RNA, Transfer
(metabolism)
- Rabbits
- Seasons
- Time Factors
- Valine
(metabolism)
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