Needle bleb revision of encapsulated filtering bleb with bevacizumab.

Abstract

The utility of needle bleb revision with bevacizumab in a patient with a failing bleb following trabeculectomy is explored. The patient had previously failed needle bleb revision with mitomycin C. After needling and injection of 1 mg of bevacizumab, the bleb was noted to be more diffuse with a decrease in surface neovascularization. Bevacizumab may be an effective medication for rescuing failing filtering blebs that exhibit neovascularization.

• Authors: Malik Y Kahook, Joel S Schuman, Robert J Noecker
• Journal: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye (Ophthalmic Surg Lasers Imaging) 2006 Mar-Apr Vol. 37 Issue 2 Pg. 148-50 ISSN: 1542-8877 [Print] United States
• PMID: 16583638 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Monoclonal
• Antibodies, Monoclonal, Humanized
• Bevacizumab

Topics

• Antibodies, Monoclonal (therapeutic use)
• Antibodies, Monoclonal, Humanized
• Bevacizumab
• Blister (drug therapy, surgery, therapy)
• Combined Modality Therapy
• Conjunctiva (blood supply, drug effects)
• Follow-Up Studies
• Glaucoma (surgery)
• Humans
• Injections
• Intraocular Pressure
• Male
• Middle Aged
• Neovascularization, Pathologic (pathology, prevention & control)
• Ocular Hypertension (drug therapy, surgery, therapy)
• Reoperation
• Trabeculectomy
• Treatment Failure