[Effect of MAGNE-B6 on the clinical and biochemical manifestations of the syndrome of attention deficit and hyperactivity in children].

Abstract

MAGNE-B6 was used for the therapy of a group of 31 children aged from 6 to 12 with attention deficiency and hyperactivity syndrome. The control group included 20 children with similar manifestations of the same pathology, which received a polyvitamin complex. The efficacy of therapy was assessed in the 30th day with the aid of a complex clinical-neuropsychological and biochemical investigations. It was established that the administration of MAGNE-B6 led to improvements in the behavior, decreased the level of anxiety and aggression, improved both large- and small-scale mobility, decreased the level of synkinesis, increased the characteristics of attention, corrected the magnesium homeostasis, and favored normalization of the blood electrolytes. Reliable differences (p < 0.01 or 0.001) between the test and control groups in the degree of expression of the indicated disorders were observed.

• Authors: O R Nogovitsina, E V Levitina
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) 2006 Jan-Feb Vol. 69 Issue 1 Pg. 74-7 ISSN: 0869-2092 [Print] Russia (Federation)
• PMID: 16579066 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Drug Combinations
• Magne B6
• Vitamin B 6
• Ca(2+) Mg(2+)-ATPase
• magnesium sodium potassium ATPase
• Sodium-Potassium-Exchanging ATPase
• Magnesium
• Ascorbic Acid
• Calcium

Topics

• Ascorbic Acid (therapeutic use)
• Attention (drug effects)
• Attention Deficit Disorder with Hyperactivity (blood, drug therapy, psychology)
• Biological Transport
• Ca(2+) Mg(2+)-ATPase (metabolism)
• Calcium (blood)
• Child
• Drug Combinations
• Erythrocytes (drug effects, metabolism)
• Female
• Humans
• Magnesium (administration & dosage, blood, therapeutic use)
• Male
• Neuropsychological Tests
• Sodium-Potassium-Exchanging ATPase (metabolism)
• Surveys and Questionnaires
• Vitamin B 6 (administration & dosage, therapeutic use)