Abstract | BACKGROUND: DESIGN: Prospective cohort study. SETTING: Pediatric intensive care unit of a tertiary care hospital in north India. PATIENTS: STUDY DESIGN: RESULTS: The median (95% confidence interval) vasopressin level at baseline in children with septic shock was 116 (63.3-130.7) pg/mL, and in children with sepsis but no shock it was 106 (61.7-131.77) pg/mL. The median value for survivors was 76 (44.6-130.9) pg/mL, and for nonsurvivors, 118 (81.7-259) pg/mL (p = .16). The serial values also did not show any significant changes; the values at 24 hrs (n = 17), 48 hrs (n = 16), and 96 hrs (n = 15) were 105 (76.1-125.9), 105 (41.4-155.5), and 109.5 (54.9-154.8) pg/mL, respectively. CONCLUSIONS: The results of our study suggest that vasopressin levels are elevated in children with septic shock and that serial values up to 96 hrs do not show any decline.
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Authors | Rakesh Lodha, Subbiah Vivekanandhan, Manjunatha Sarthi, Sushil K Kabra |
Journal | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
(Pediatr Crit Care Med)
Vol. 7
Issue 3
Pg. 220-4
(May 2006)
ISSN: 1529-7535 [Print] United States |
PMID | 16575349
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Chi-Square Distribution
- Child
- Child, Preschool
- Female
- Humans
- Infant
- Male
- Prospective Studies
- Shock, Septic
(blood)
- Statistics, Nonparametric
- Vasopressins
(blood)
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